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Question
arrange in the proper sequence the following events as they occur in the ossification of a long bone. 1. chondroblasts die, and the surrounding matrix breaks down. 2. osteoblasts secrete osteoid. 3. blood vessels transport osteoblasts into the area to be ossified. 4. chondroblasts create a model of long bones from cartilage. 5. osteoblasts become osteocytes. 3,2,1,5,4 4,1,3,2,5 5,2,3,1,4 4,1,5,3,2 3,2,5,4,1
Brief Explanations
- The process starts with chondroblasts forming a cartilage model of the long bone (step 4).
- The chondroblasts then die, and the cartilage matrix breaks down (step 1).
- Blood vessels bring osteoblasts to the area (step 3).
- Osteoblasts secrete osteoid, the organic bone matrix (step 2).
- Finally, osteoblasts get trapped in the matrix and mature into osteocytes (step 5).
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4, 1, 3, 2, 5