Question

if a chemical that inhibits enzyme #3 was added to the system containing the biochemical pathway illustrated in the animation, which of the following would result?
check all that apply
product #1 would accumulate in the system.
product #2 would accumulate in the system.
substrate #1 would accumulate in the system.
substrate #1 would become depleted.
substrate #3 would accumulate in the system.

Explanation:

In a biochemical pathway, when an enzyme is inhibited, the substrate of that enzyme accumulates as it cannot be converted further. Enzyme #3 acts on Substrate #3 to convert it into a product. With Enzyme #3 inhibited, Substrate #3 cannot be processed further and will accumulate. Also, the products of previous steps (assuming the pathway is sequential) will not be affected in terms of accumulation due to this specific enzyme - 3 inhibition. Product #1 and Product #2 are from earlier steps and their production and consumption are not directly related to Enzyme #3 inhibition. Substrate #1 is also from an earlier step and its levels are not directly affected by Enzyme #3 inhibition. Since Substrate #3 cannot be converted further, it will accumulate.

Answer:

Substrate #3 would accumulate in the system.