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Question
many different types of mutations can occur within the body. cystic fibrosis is a genetic disorder that is caused by different mutations within the cftr gene. one mutation in the cftr gene that leads to cystic fibrosis causes translation to end earlier in the gene sequence. which type of mutation causes this translation stop that leads to cystic fibrosis?
select
missense
nonsense
ndeletion
A nonsense mutation creates a premature stop - codon in the mRNA sequence during translation, leading to a truncated and often non - functional protein. Cystic fibrosis caused by a mutation that leads to an early translation stop is due to a nonsense mutation.
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C. nonsense