Question

multiple choice question
damage to endothelium and exposure of underlying collagen in blood vessel walls trigger the ______ clotting mechanism of coagulation.
o extrinsic
o contact - dependent
o intrinsic
o immediate

Explanation:

When the endothelium of blood - vessel walls is damaged and the underlying collagen is exposed, it activates the intrinsic clotting mechanism. The intrinsic pathway is initiated by contact - activation on the surface of negatively charged substances like collagen. The extrinsic pathway is triggered by tissue factor released from damaged tissue cells. Contact - dependent is a part of the intrinsic pathway description and "immediate" is not a standard term for a clotting mechanism in this context.

Answer:

C. intrinsic