Question

multiple choice question required ochronosis is caused by the accumulation of which substance? please select your answer... a homogentisic acid b calcium pyrophosphate c hydroxyapatite d uric acid

Explanation:

Ochronosis is a rare genetic disorder characterized by the accumulation of homogentisic acid due to a deficiency in the enzyme homogentisate 1,2 - dioxygenase. This leads to the dark - colored pigmentation of connective tissues and other symptoms.

Answer:

A. Homogentisic acid