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question 15 6 parts -- of 2 points nucleoplasmin is a nuclear protein. this protein was divided into two segments and linked to the same large cytoplasmic protein, generating two fusion proteins. after injecting these fusion proteins into a cell, one of the proteins was found in the nucleus and the other in the cytoplasm. which of the following conclusions can be drawn from these results? nucleoplasmin does not have a nuclear localization signal. the cytoplasmic protein contains a nuclear localization signal. one of the fusion proteins entered the nucleus by passive transport.
Nucleoplasmin is a nuclear - protein. Proteins with a nuclear localization signal are actively transported into the nucleus. If a protein enters the nucleus by passive transport, it likely lacks a nuclear localization signal. The options suggest different scenarios related to the presence or absence of such signals in fusion proteins. The key concept is that proteins with nuclear localization signals are targeted to the nucleus and those without may not be.
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The answer is "Nucleoplasmin does not have a nuclear localization signal." because if one of the fusion proteins entered the nucleus by passive transport, it implies that it does not have the specific signal required for active nuclear import which is characteristic of proteins that are supposed to be in the nucleus like nucleoplasmin.