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Question
scenario: a patient with a history of alcohol use disorder and bipolar disorder is being considered for a mood stabilizer. question: which medication should be avoided due to potential hepatotoxicity? lithium. valproate. lamotrigine. carbamazepine.
Valproate (also known as valproic acid or divalproex sodium) is known to have potential hepatotoxic (liver - damaging) effects. Patients with a history of alcohol use disorder already have a higher risk of liver problems due to alcohol - related liver damage. Lithium, lamotrigine, and carbamazepine have less of a risk of hepatotoxicity compared to valproate in this context.
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B. Valproate