Question

the synthetic molecule atpγs resembles atp structurally, but with one very important difference: the phosphate - groups of atpγs cannot be removed. thus, while atpγs can bind to molecules just like atp, it cannot be dephosphorylated. experimentally, it is possible to replace all the atp in a cell with atpγs. what effect would atpγs likely have on movement of vesicles from the endomembrane system?

○ atpγs would hyperactivate kinesin, and vesicle transport would speed up.
○ atpγs would have no effect on kinesin, and vesicular transport would not change.
○ atpγs would not allow kinesin to change shape, and thus vesicular transport would stop.

Explanation:

Kinesin uses the energy from ATP hydrolysis (dephosphorylation) to change shape and move vesicles. Since ATPγS cannot be dephosphorylated, it won't provide the necessary energy for kinesin to change shape and carry out vesicular transport.

Answer:

ATPγS would not allow kinesin to change shape, and thus vesicular transport would stop.