Question

the underlying cause of tay-sachs disease is ________. answer the muscle cells store excess lipids the ingestion of excess lipids in the diet the lack of sufficient lysosomes in the nervous system the lysosomes lack an enzyme needed to break down a specific glycolipid in nerve cell membranes i dont know yet

Explanation:

Tay - Sachs disease is a lysosomal storage disorder. Lysosomes contain enzymes for breaking down various substances. In Tay - Sachs, lysosomes lack the enzyme hexosaminidase A, which is needed to break down a specific glycolipid (ganglioside GM2) in nerve cell membranes. The first option is incorrect as muscle cells don't store excess lipids in this context. The second option is wrong because it's not due to dietary lipid ingestion. The third option is incorrect as it's not about the lack of lysosomes but the lack of a specific enzyme in lysosomes.

Answer:

the lysosomes lack an enzyme needed to break down a specific glycolipid in nerve cell membranes