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what cells make it possible for immune cells to cross the blood - brain barrier? enter the answer check it
Endothelial cells that form the blood - brain barrier can become activated under certain conditions, and pericytes and astrocytes also play roles in modulating the permeability to allow immune cell passage. Microglia can also interact with immune cells at the barrier. However, specialized high - endothelial venule (HEV) like structures formed by activated endothelial cells are key in facilitating immune cell transmigration across the blood - brain barrier during inflammation.
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Activated endothelial cells (with contributions from pericytes, astrocytes and microglia in the process)