Question

what is the probability that a female child of charles and marie would suffer from hemophilia? 0 percent 25 percent 50 percent 100 percent

Explanation:

Step1: Identify the genotypes of parents

Charles has genotype $X^{H}Y$ and Marie has genotype $X^{H}X^{h}$.

Step2: Determine possible genotypes of female offspring

The possible genotypes of female offspring are obtained by combining the X - chromosomes from each parent. The possible combinations are $X^{H}X^{H}$ (from $X^{H}$ of father and $X^{H}$ of mother) and $X^{H}X^{h}$ (from $X^{H}$ of father and $X^{h}$ of mother).

Step3: Recall the inheritance pattern of hemophilia

Hemophilia is an X - linked recessive disorder. A female needs to have two copies of the recessive allele ($X^{h}X^{h}$) to be affected. Since the possible genotypes of female offspring of Charles and Marie are $X^{H}X^{H}$ and $X^{H}X^{h}$, no female offspring will have the $X^{h}X^{h}$ genotype.

Answer:

A. 0 percent