Question

what is the significance of the nuclear envelope disintegrating during prophase? a. it permits spindle fibers to access chromosomes. b. it marks the end of mitosis. c. it allows the nucleus to divide into two. d. it triggers the cell to enter cytokinesis.

Explanation:

During prophase of mitosis, nuclear envelope disintegration allows spindle - fibers to access chromosomes for proper chromosome segregation.

Answer:

a. It permits spindle fibers to access chromosomes.