Question

enzymes only work with specific substrates because each enzyme: can change the temperature and ph around them has an active site which only fits substrates with a particular shape becomes denatured when it is heated can only make ionic bonds clear my selection

Explanation:

Enzymes have an active - site with a specific shape that only accommodates substrates of a particular shape, which is why they are specific to certain substrates. Other options do not explain substrate - specificity.

Answer:

Has an active site which only fits substrates with a particular shape