QUESTION IMAGE
Question
father
%kids expressing huntingtons=
%kids without huntingtons=
mother
= h = h = hh = hh = 0% = 25% = 50%
Step1: Identify parental genotypes
Huntington's disease is an autosomal dominant disorder, so the affected parent (father) has genotype $Hh$, and the unaffected mother has genotype $hh$.
Father's gametes: $H$, $h$
Mother's gametes: $h$, $h$
Step2: Fill Punnett square
| Father\Mother | $H$ | $h$ |
|---|---|---|
| $h$ | $Hh$ | $hh$ |
Step3: Calculate trait percentages
- % with Huntington's ($Hh$): $\frac{2}{4} \times 100\% = 50\%$
- % without Huntington's ($hh$): $\frac{2}{4} \times 100\% = 50\%$
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- Father's genotype: $Hh$
- Mother's genotype: $hh$
- Punnett square cells (top-left, top-right, bottom-left, bottom-right): $Hh$, $hh$, $Hh$, $hh$
- %Kids expressing Huntington's: 50%
- %Kids without Huntington's: 50%