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Question
how you ranked the treatments: 1. isotonic saline 2. hypertonic saline 3. hypotonic saline you have chosen isotonic saline. predict the effects of your treatment on the following: blood sodium concentration initial value 114 (low) decrease no change increase brain matrix pressure 27 (high) neuron firing rate 4.5 (high) net free water movement initial value out of vessel into vessel in equilibrium out of vessel justify your answer for net free water movement.
Step1: Understand isotonic saline
Isotonic saline has same osmolarity as blood.
Step2: Effect on blood sodium concentration
Since isotonic, no net movement of sodium - no change.
Step3: Effect on brain matrix pressure
Reduces high pressure as it doesn't cause further fluid shifts in a harmful way - decrease.
Step4: Effect on neuron firing rate
Normalizes high rate by stabilizing ion balance - decrease.
Step5: Effect on net free water movement
In isotonic condition, water movement reaches equilibrium.
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Blood Sodium Concentration: No Change
Brain Matrix Pressure: Decrease
Neuron Firing Rate: Decrease
Net Free Water Movement: In Equilibrium
Justification for net free water movement: Isotonic saline has the same osmotic pressure as the body's fluids. So, there is no net driving force for water to move into or out of the vessels, resulting in an equilibrium state of water movement.