Question

many different types of mutations can occur within the body. cystic fibrosis is a genetic disorder that is caused by different mutations within the cftr gene. one mutation in the cftr gene that leads to cystic fibrosis causes translation to end earlier in the gene sequence. which type of mutation causes this translation error that leads to cystic fibrosis?

• silent
• missense
• nonsense
• deletion

Explanation:

A nonsense mutation creates a premature stop - codon, causing translation to end earlier. Silent mutations don't change the amino - acid sequence, missense mutations change one amino - acid, and deletions involve the removal of nucleotides.

Answer:

C. nonsense