Question

misusing prescription drugs can
only lead to mild side - effects
lower the risk of dependence
lead to negative psychological effects
only harm to people if they are very ill

Explanation:

Misusing prescription drugs can have various negative impacts including serious side - effects, increased risk of dependence, and negative psychological effects. It doesn't just cause mild side - effects, doesn't lower the risk of dependence, and doesn't only harm if large amounts are used.

Answer:

lead to negative psychological effects