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Question
part a
the following is a hypothetical pedigree for a family, some of whose members have symptoms of leigh syndrome, caused by an mtdna mutation that reduces atpase activity. assume the mutation is fully penetrant.
a = ataxia (loss of motor function)
p = peripheral neuropathy
which of the six individuals in the last generation would transmit the condition to their offspring?
all of the individuals with the disorder
all six individuals of the last generation
all of the women with the disorder
all of the women in the last generation
all of the individuals with a mother that has the disorder
Leigh syndrome is caused by an mt - DNA mutation. mt - DNA is maternally inherited. So, all individuals with a mother that has the disorder will inherit the mutation and potentially transmit the condition to their offspring.
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all of the individuals with a mother that has the disorder