Question

read about how transcription factors are involved in a negative feedback loop that helps the human body maintain homeostasis, or a state of internal stability.
pancreatic tissue under a microscope
when blood glucose levels rise, like after a big meal, transcription factors are typically triggered to bind to a specific dna sequence on chromosome 11 inside pancreatic beta cells. as a result, the transcription rate of the insulin gene increases, producing more insulin proteins. the beta cells then secrete the proteins into the blood, which signals cells to take up glucose, which lowers blood glucose levels. once blood glucose levels decrease, the rate of insulin gene transcription decreases.
select the true statements.
insulin gene transcription occurs at a constant rate in beta cells.
transcription can be controlled by transcription factors to meet an organisms needs.
insulin gene transcription is regulated by blood glucose levels.
chromosome 11, which contains the insulin gene, is unique to beta cells.

Explanation:

1. The text states insulin gene transcription slows when blood glucose drops, so it is not constant.
2. Transcription factors adjust insulin gene transcription to regulate blood glucose, matching the body's needs.
3. Blood glucose levels trigger transcription factor activity, which controls insulin gene transcription rates.
4. All human body cells contain the same set of chromosomes, so chromosome 11 is not unique to beta cells.

Answer:

• Transcription can be controlled by transcription factors to meet an organism's needs.
• Insulin gene transcription is regulated by blood glucose levels.