Question

select the correct answer.
which mutation does the given change in nucleotide sequence represent?
attgcatc → atacgttc
a. translocation
b. substitution
c. inversion
d. duplication

Explanation:

1. Translocation: Moves DNA between non-homologous chromosomes; not seen here.
2. Substitution: Replaces one nucleotide with another; this does not match the multi-base rearrangement observed.
3. Inversion: Reverses a segment of nucleotides. Comparing the original sequence ATTGCATC to the mutated ATACGTTC, the segment TGC (positions 3-5 of original) is reversed to CGT (positions 3-5 of mutated), which fits this mutation type.
4. Duplication: Repeats a DNA segment; no duplication is present here.

Answer:

C. inversion