Question

some factors can change the shape of an enzyme and when an enzyme’s shape has changed it no longer works. when this happens we say that the enzyme has been ——. options: altered, denatured, renatured, modified

Explanation:

Enzymes are proteins, and when factors like temperature or pH change their specific three - dimensional structure (especially the active site), this process is called denaturation. Denaturation causes the enzyme to lose its catalytic activity. The term "denatured" specifically refers to this loss of the native structure and function of the enzyme due to structural change. "Altered" and "modified" are too general, and "renatured" refers to the restoration of the native structure (which is not what happens here as the question implies the enzyme no longer works after the shape change).

Answer:

denatured