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Question
which of the following medication classes should be avoided in patients with acute or chronic bronchitis because it will contribute to ventilation - perfusion mismatch in the patient? xanthines antihistimines steroids anticholinergics
Antihistamines can dry up secretions and thicken mucus in patients with bronchitis. This can lead to ventilation - perfusion mismatch as the air - blood exchange in the lungs is affected. Steroids reduce inflammation, xanthines can improve airway function, and anticholinergics can relax airway smooth muscles, none of which typically cause significant ventilation - perfusion mismatch in the context of bronchitis like antihistamines can.
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Antihistamines