Question

which of the following medications have protocols that require clients to meet specific risk - management criteria and sign a treatment agreement before the nurse can administer the medication?
lubiprostone
azathioprine
sulfasalazine
alosetron

Explanation:

Alosetron is a medication for severe irritable bowel syndrome with diarrhea (IBS-D) in women, and it has strict risk-management protocols. Due to serious gastrointestinal risks (like ischemic colitis), patients must meet specific criteria, sign a treatment agreement, and be enrolled in a restricted access program before administration. The other medications listed do not require this specific structured risk-management agreement process.

Answer:

D. Alosetron