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Question
- what is a mutation and what may cause them?
A mutation is a permanent change in the DNA sequence of a gene, chromosome, or genome. Causes include: 1) Spontaneous errors during DNA replication (e.g., base mispairing). 2) Chemical mutagens (e.g., benzene, formaldehyde) that alter DNA structure. 3) Physical mutagens (e.g., UV radiation, X - rays) that damage DNA (e.g., UV causes thymine dimers). 4) Biological agents (e.g., some viruses like HPV can integrate into host DNA and disrupt sequences). Also, transposable elements (jumping genes) can move within the genome and cause mutations.
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A mutation is a permanent change in the DNA sequence (of a gene, chromosome, or genome). Causes include spontaneous DNA replication errors, chemical mutagens (e.g., benzene), physical mutagens (e.g., UV/X - rays), biological agents (e.g., certain viruses), and transposable elements.