Question

this is considered the most harmful type of gene mutation. it occurs when the codon reading frame is shifted and creates a chain reaction of errors in amino acids. insertion frameshift deletion duplication

Explanation:

The description refers to a gene mutation that shifts the codon reading frame, causing a chain reaction of errors in amino acids. Frameshift mutations occur due to insertions or deletions of nucleotides that are not in multiples of three, disrupting the reading frame. The option "Frameshift" matches this description as it's the type of mutation where the reading frame is shifted, leading to extensive changes in the amino acid sequence.

Answer:

Frameshift