Question

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a nurse is planning care for a client who has a new prescription for methotrexate. the nurse should plan to monitor the client for which of the following adverse effects?

• bone marrow depression
• thrombocythemia
• double vision
• constipation

Explanation:

Methotrexate is an antimetabolite used in chemotherapy and for other conditions. A well - known adverse effect of methotrexate is bone marrow depression, which leads to decreased production of blood cells. Thrombocythemia (increased platelets) is not an adverse effect of methotrexate; rather, it can cause thrombocytopenia (decreased platelets) as part of bone marrow depression. Double vision is not a typical adverse effect of methotrexate. Constipation is also not a common adverse effect associated with methotrexate use.

Answer:

A. Bone marrow depression