Question

what is the problem with treating pernicious anemia with only folate?

Explanation:

Pernicious anemia is caused by a deficiency of vitamin B12, not just folate. Folate can correct the megaloblastic anemia symptoms but not the neurological deficits associated with vitamin B12 deficiency. Neurological damage may progress if only folate is used for treatment.

Answer:

Folate treatment can correct the anemia symptoms but not the neurological deficits, and neurological damage may progress.