Question

discussion questions: 1. on the diagram above, mark the locations of these events. use the letters provided. a - diapedesis b - edema c - release of histamines & kinins 2. the cardinal signs of inflammation are listed below. for each sign, explain why it happens and how it relates to the healing process. cardinal sign redness heat pain swelling histamines & kinins cause blood vessel dilation why it happens dilated blood vessels allow leukocytes to arrive quickly why its necessary for healing

Explanation:

1. A - diapedesis is the process by which leukocytes (white - blood cells) move from the blood vessels into the surrounding tissue. This is marked as the movement of phagocytes to the area. B - edema is caused by increased permeability of blood vessels allowing fluid to leak out, which is related to the dilation and increased leakiness of local blood vessels. C - release of histamines & kinins causes blood vessel dilation as histamines act on blood vessels to make them expand.
2. Histamines and kinins cause blood vessel dilation to increase blood flow to the injured area. This brings more immune cells and nutrients necessary for healing. Dilated blood vessels allow leukocytes to arrive quickly because the increased blood flow and vessel permeability make it easier for them to reach the site of injury. The presence of immune cells like phagocytes helps in consuming bacteria and cell debris, which is crucial for tissue repair.

Answer:

1. A - Diapedesis: Movement of phagocytes to the area. B - Edema: Dilation and increased leakiness of local blood vessels. C - Release of histamines & kinins: Histamines cause blood vessel dilation.
2. Histamines & kinins cause dilation to increase blood - flow for healing. Dilated vessels aid leukocyte arrival for tissue repair.