Question

multiple choice 2 points
how can you determine if two substituents on a cyclohexane ring are in a cis or trans conformation?
by calculating the molecular weight of the substituents.
by checking if they are both in axial positions.
by observing if they face the same or opposite directions on the molecule.
by measuring the bond angles between them.

Explanation:

In cis - trans isomerism, cis means the substituents are on the same side (face the same direction) and trans means they are on opposite sides (face opposite directions) of the cyclohexane ring. Molecular weight, axial positions, and bond - angles are not used to determine cis - trans isomerism.

Answer:

C. By observing if they face the same or opposite directions on the molecule.