Question

a nurse is caring for a client who is taking warfarin and has a new prescription for trimethoprim/sulfamethoxazole to treat a urinary tract infection. the nurse should clarify the prescriptions with the provider because taking these two medications concurrently can increase the clients risk for which of the following?

• bleeding
• thrombosis
• ecg changes
• ototoxicity

Explanation:

Warfarin is an anticoagulant that slows blood clotting. Trimethoprim/sulfamethoxazole can enhance the anticoagulant effect of warfarin by affecting its metabolism and reducing vitamin K availability, which increases bleeding risk. Thrombosis is a clotting risk, which warfarin prevents; ECG changes and ototoxicity are not key interactions between these two drugs.

Answer:

Bleeding