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Question
proton pump inhibitors available in slow release dosage forms may be crushed. chewed. broken. sprinkled on applesauce.
Proton pump inhibitors (PPIs) in slow - release dosage forms are designed to release the drug gradually. Crushing, chewing, or breaking them would disrupt the slow - release mechanism. However, some PPIs in slow - release (or delayed - release) dosage forms can be opened and the granules sprinkled on applesauce (a soft food) for administration, especially for patients who have difficulty swallowing whole tablets, as long as the granules are not crushed or chewed. The other options (crushed, chewed, broken) would interfere with the intended drug release profile.
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D. sprinkled on applesauce