Question

question 2
what is the correct notation for patients as karyotype?
a 46, xx
b 46, xy
c 47, xx, +21
d 47, xx, -21
e 46, xx, +21
question 3
what disease or disorder would you say patient a has?
a klinefelters syndrome
b downs syndrome
c turners syndrome
d triplo xxx
e patau syndrome
f edwards syndrome

Explanation:

For Question 2, a normal female karyotype has 46 chromosomes with two X - chromosomes (46, XX). A normal male has 46 chromosomes with one X and one Y chromosome (46, XY). An extra copy of chromosome 21 (47, XX, +21) is characteristic of Down's Syndrome. The notation 47, XX, -21 is incorrect as it implies a missing chromosome 21 and 46, xx, +21 has incorrect case for chromosome notation.
For Question 3, Down's Syndrome is caused by trisomy 21 (an extra copy of chromosome 21). Klinefelter's Syndrome is 47, XXY in males. Turner's Syndrome is 45, X. Triplo XXX has three X - chromosomes (47, XXX). Patau Syndrome is trisomy 13 and Edward's Syndrome is trisomy 18.

Answer:

Question 2: A. 46, XX
Question 3: B. Down's Syndrome