Question

smooth endoplasmic reticulum
does not have ribosomes on the membrane and makes glucose for the cell.
has ribosomes on the membrane and gets rid of waste inside the cell.
does not have ribosomes on the membrane and helps remove harmful substances from a cell.
has ribosomes on the membrane and makes proteins for the cell.

Explanation:

The smooth endoplasmic reticulum lacks ribosomes on its membrane. One of its main functions is detoxification, helping to remove harmful substances from a cell. It is not involved in making glucose for the cell, nor does it have ribosomes on its membrane (that's the rough endoplasmic reticulum's characteristic).

Answer:

does not have ribosomes on the membrane and helps remove harmful substances from a cell.