Question

what is the definitive test for pernicious anemia?

Explanation:

Pernicious anemia is related to vitamin - B12 deficiency due to lack of intrinsic factor. The Schilling test was once the definitive test but has been largely replaced. Currently, measurement of serum vitamin B12 levels, along with testing for anti - intrinsic factor and anti - parietal cell antibodies, are important diagnostic steps. However, the combination of low vitamin B12 levels, presence of relevant antibodies, and typical clinical features can be considered definitive.

Answer:

Measurement of serum vitamin B12 levels along with testing for anti - intrinsic factor and anti - parietal cell antibodies, combined with clinical features.