Question

what problem happens when pyruvate is produced in glycolysis and nad+ is turned into nadh?
increased nadh disrupts the glycolytic pathway.
excess pyruvate inhibits glycolytic enzymes.
accumulation of atp leads to glycolysis shutdown.
depletion of nad+ halts glycolysis.

Explanation:

Glycolysis requires NAD+ as an electron - acceptor. When NAD+ is converted to NADH without being recycled back to NAD+, the lack of NAD+ halts the glycolytic reactions that require it.

Answer:

Depletion of NAD+ halts glycolysis.