Question

1. what unique property of the estrogen receptor allows for its identification and purification? √2,4

Explanation:

The estrogen receptor is a ligand-binding protein that has a high, specific affinity for estrogen molecules (like estradiol). This selective, strong binding property allows researchers to use labeled estrogen ligands (such as radioactively tagged estradiol) to identify the receptor in biological samples, and to purify it by leveraging this specific binding interaction (e.g., using affinity chromatography with immobilized estrogens).

Answer:

The estrogen receptor has a high, specific affinity for estrogen ligands (such as estradiol). This unique, selective binding ability allows researchers to use labeled estrogen molecules to identify the receptor in samples, and to purify it via methods like affinity chromatography that rely on this specific binding interaction.