Question

which type of mutation is shown in the right panel? normal dna and mrna a g a c c a c g a t t c a g a c c a g g a t t c u c u g g u g c u a a g u c u g g u c c u a a g ser gly ala lys ser gly pro lys 3 of 4 questions frameshift mutation nonsense mutation missense mutation silent mutation

Explanation:

1. Frameshift mutation: Involves insertion/deletion of nucleotides that shifts the reading frame, changing multiple amino acids. This is not the case here, as only one amino acid is altered.
2. Nonsense mutation: Changes a codon to a stop codon, prematurely terminating the protein. No stop codon is introduced here.
3. Missense mutation: A single nucleotide change that alters one codon, leading to a different amino acid in the protein sequence. In the right panel, the DNA sequence changes from CGA to GGA, which changes the mRNA codon from GCU (coding for Alanine/Ala) to CCU (coding for Proline/Pro), matching this definition.
4. Silent mutation: A nucleotide change that does not alter the encoded amino acid. This is not the case here, as the amino acid changes.

Answer:

Missense mutation