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Question
7 arsenic poisoning can lead to organ failure and death. though arsenic can inhibit or interfere with a number of cellular enzymes, arsenic poisoning is thought to be mainly due to indirect inhibition of enzymes involved in both pyruvate oxidation and the citric acid cycle. as a result, this compound must be able to enter which cellular compartment? multiple choice the intermembrane space of the mitochondria the mitochondrial matrix the cytoplasm the nucleus the endoplasmic reticulum
Pyruvate oxidation and the Citric - acid cycle occur in the mitochondrial matrix. For arsenic to inhibit enzymes involved in these processes, it must enter the mitochondrial matrix.
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B. The mitochondrial matrix