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Question
- based on the human blood groups, there are 8 kinds of blood types. for each blood type, determine which antigens or antibodies are based on the red blood cells. also, determine which antibodies are present in plasma.
- how do you determine what blood group a person belongs?
- what is agglutination?
- what problems arise when agglutination occurs after a blood transfusion?
- people with which blood group are considered universal donors? why is this so?
- people with which blood group are considered universal receivers? why is this so?
- study the chart and answer the following questions:
a. can a person with o rh - receive o rh + blood?
b. a person with a rh + blood can receive blood from people with which blood group(s)?
c. a person with b rh - blood can donate to people with which blood group(s)?
d. a person with ab rh - can receive blood from people with which blood group(s)?
- Blood - grouping is determined by the presence or absence of specific antigens (A, B, Rh) on red - blood cells. A sample of blood is mixed with antibodies against A, B, and Rh antigens. Agglutination (clumping) indicates the presence of the corresponding antigen.
- Agglutination is the clumping together of red - blood cells. It occurs when antibodies in the plasma bind to antigens on the surface of red - blood cells.
- When agglutination occurs after a blood transfusion, it can lead to blockage of small blood vessels, hemolysis (rupture of red - blood cells), release of hemoglobin into the bloodstream, kidney damage, and potentially life - threatening complications.
- People with blood group O are considered universal donors. This is because their blood lacks A and B antigens, so it can be given to recipients with A, B, AB, or O blood groups without triggering an immune response due to A or B antigens.
- People with blood group AB are considered universal recipients. They have both A and B antigens on their red - blood cells, so they do not have antibodies against A or B in their plasma. Thus, they can receive blood from donors with A, B, AB, or O blood groups.
15a. A person with O Rh+ can receive O Rh - blood. The Rh - blood does not have the Rh antigen, so it will not cause an immune reaction in an Rh+ individual.
15b. A person with A Rh+ can receive blood from A Rh+, A Rh -, O Rh+, and O Rh - donors. A - type blood has A antigens, and O - type blood has no A or B antigens, and Rh+ individuals can receive Rh - blood in most cases.
15c. A person with B Rh - can donate to B Rh - and B Rh+ individuals, as well as AB Rh - and AB Rh+ individuals. B - type blood has B antigens, and these recipients can tolerate the B antigen.
15d. A person with AB Rh+ can receive blood from A Rh+, A Rh -, B Rh+, B Rh -, AB Rh+, AB Rh -, O Rh+, and O Rh - donors.
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- By testing for A, B, and Rh antigens using antibodies.
- Clumping of red - blood cells due to antibody - antigen binding.
- Vascular blockage, hemolysis, kidney damage, etc.
- O blood group; lacks A and B antigens.
- AB blood group; has both A and B antigens and no anti - A or anti - B antibodies.
15a. Yes.
15b. A Rh+, A Rh -, O Rh+, O Rh -.
15c. B Rh -, B Rh+, AB Rh -, AB Rh+.
15d. A Rh+, A Rh -, B Rh+, B Rh -, AB Rh+, AB Rh -, O Rh+, O Rh -.