Question

lily, a 20 - year - old female, came into the clinic a month ago exhibiting symptoms such as tremors, liver dysfunction, and psychiatric disturbances. after multiple lab tests, she was diagnosed with wilson’s disease. this disease renders atp7b protein dysfunctional, which leads to copper accumulation within liver cells. this copper overload results in oxidative damage to the liver and impaired processing/transport. these cellular disruptions contribute to the broader symptoms of wilson’s disease, including liver dysfunction and neurological problems. which organelle has malfunctioned?

Explanation:

Step1: Identify the key - molecule

The key molecule is ATP7B protein which is related to copper transport.

Step2: Recall organelle function

The Golgi apparatus is involved in protein processing and transport. Since ATP7B protein is dysfunctional and related to transport, and copper accumulation occurs due to its malfunction, it implies a problem with the organelle related to protein transport. The Golgi apparatus modifies, sorts, and packages proteins for secretion or use within the cell. A malfunction in the Golgi - related processes of the ATP7B protein can lead to the described copper accumulation and subsequent symptoms.

Answer:

Golgi apparatus