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Question
squid are marine animals and have a huge nerve cell that runs the length of their body. researchers have been able to study vesicle transport by opening up these cells, squeezing out the contents, focusing videomicroscopes on microtubules that run the length of the cell, and recording how vesicles move in real - time. the next several questions ask you to make predictions about this system. suppose you added vesicles to the system that lacked zip code proteins in their membrane. predict what would happen. the vesicles would not be able to move, because kinesin would not attach to microtubules properly. the vesicles would move, but would not fuse with the membrane at their destination. the vesicles would not be able to move, because kinesin would not attach to them properly. in the \squeezed out nerve cell\ study system, mitochondria are no longer producing atp. vesicle movement continues for a while in the study preparation that is under the videomicroscope, but then stops. why? choose the single best answer. vesicles detach from kinesin so just float around or stay still. microtubules disintegrate so kinesin has nothing to walk on. atp runs out so kinesin cant be phosphorylated and cant walk.
- Zip - code proteins are important for kinesin attachment to vesicles for their movement. Without them, kinesin cannot attach properly to vesicles, preventing their movement.
- Kinesin - based vesicle movement requires ATP for phosphorylation to enable its "walking" on microtubules. When mitochondria stop producing ATP, kinesin can't be phosphorylated and movement stops.
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- C. The vesicles would not be able to move, because kinesin would not attach to them properly.
- C. ATP runs out so kinesin can't be phosphorylated and can't walk.