Question

______9. what is the most likely genotype of individual \c\? (ff, ff or ff?)

a typical pedigree for a family that carries falconi anemia. note that carriers are not indicated with half - colored shapes in this chart.

analysis questions.
to answer questions #1 - 5, use the letter \f\ to indicate the recessive falconi anemia allele, and the letter \f\ for the normal allele.

1. what is arlenes genotype?
2. what is georges genotype?
3. what are ann & michaels genotypes?
4. most likely, sandras genotype is.
5. list three people from the chart (other than george) who are most likely carriers of falconi anemia.

Explanation:

Step1: Identify affected genotype

Falconi anemia is recessive, so affected individuals have genotype $ff$.

Step2: Determine Arlene's genotype

Arlene is affected (shaded circle), so her genotype is $ff$.

Step3: Determine George's genotype

George is unaffected, but he has a child (Tom) with $ff$. Arlene can only pass $f$, so George must pass $f$ to Tom. Thus George is $Ff$.

Step4: Determine Ann & Michael's genotypes

Their child Carla is $ff$, so both Ann and Michael must pass $f$. They are unaffected, so their genotypes are $Ff$.

Step5: Determine Sandra's genotype

Sandra's child Daniel is $Ff$, and Tom (Sandra's partner) is $ff$. Tom can only pass $f$, so Sandra must pass $F$ to Daniel. Sandra is unaffected, so her most likely genotype is $FF$.

Step6: Identify carrier individuals

Carriers are $Ff$ (unaffected but can pass $f$). We know Sam is $Ff$, Ann is $Ff$, Michael is $Ff$; also Daniel is $Ff$, and Tina is likely a carrier (since Alan is $Ff$ and Christopher is unaffected but could receive $f$ from Tina).

Answer:

1. $ff$
2. $Ff$
3. Ann: $Ff$; Michael: $Ff$
4. $FF$
5. Sam, Ann, Michael (or Daniel, Tina as alternative valid choices)