Question

charles darwin came up with this theory of \change over time\.
population bottleneck
frequency
evolution
natural selection
gene flow
variation
founder effect
genetic drift

Explanation:

Charles Darwin is known for the theory of evolution, which describes the change in species over time. Natural selection is a mechanism of evolution, but the overarching theory of "change over time" in species is evolution. The other options (Population Bottleneck, Frequency, Gene Flow, Variation, Founder Effect, Genetic Drift) are related to evolutionary processes or concepts but not the main theory of change over time that Darwin is associated with in this context.

Answer:

Evolution