Question

dna replication review
directions: drag the cards below to fill in the blanks in the paragraph about dna replication.
helicase dna primase topoisomerase okazaki fragments dna polymerase enzymes lagging strand leading strand ligase
there are many involved in dna replication. unwinds the dna strand while breaks the hydrogen bonds between bases. lays down an rna primer that lets know where to begin adding new nucleotides.
the is made continuously, while the is made in fragments called . these fragments are glued together by

Explanation:

1. First blank: DNA replication involves multiple "enzymes" (since helicase, primase, etc., are all enzymes).
2. Second blank: "Topoisomerase" helps in unwinding the DNA strand (relieving supercoiling).
3. Third blank: "Helicase" breaks hydrogen bonds between DNA bases to separate strands.
4. Fourth blank: "DNA primase" lays down an RNA primer.
5. Fifth blank: "DNA polymerase" adds new nucleotides (needs the primer to start).
6. Sixth blank: "Leading strand" is synthesized continuously.
7. Seventh blank: "Lagging strand" is synthesized in fragments.
8. Eighth blank: The fragments of the lagging strand are "Okazaki fragments".
9. Ninth blank: "Ligase" joins (glues) the Okazaki fragments.

Answer:

1. enzymes
2. Topoisomerase
3. helicase
4. DNA primase
5. DNA polymerase
6. leading strand
7. lagging strand
8. Okazaki fragments
9. ligase