Question

epigenetics webquest: use the links (posted on schoology) to answer the following questions.
the epigenome at a glance: http://learn.genetics.utah.edu/content/epigenetics/intro/ (link 1)

1. dna is wrapped around ____________ called histones.
2. the epigenome determines the physical ____________ of the genome (set of genes in the chromosomes).
3. the epigenome ____________ around inactive genes, making them unreadable.
4. the epigenome ____________ active genes, making them accessible and readable.
5. true or false: our genome (dna) doesnt change but the epigenome is flexible and can change.
6. epigenetic tags react to environmental signals such as __________ and __________

Explanation:

These answers are based on core concepts of epigenetics, specifically from the educational resource linked.

1. DNA is structurally wrapped around histone proteins to form chromatin.
2. The epigenome controls which genes are expressed, defining the physical accessibility/expression state of the genome.
3. Tight wrapping of the epigenome around inactive genes hides them from transcription machinery.
4. Loose wrapping keeps active genes exposed for transcription factors to access.
5. The DNA sequence (genome) is stable, while epigenetic markers respond to environmental cues to change gene expression.
6. Epigenetic tags respond to common environmental signals that impact gene regulation.

Answer:

1. proteins
2. accessibility/expression state
3. wraps tightly
4. wraps loosely
5. TRUE
6. diet, stress (examples of valid environmental signals)