Question

select the correct answer.
a model cell with damaged dna was created to explain the importance of checkpoints in a cell cycle. the g2 checkpoint accidentally failed to work during experimentation. what do you think is the likely consequence of this failure?
a. the cell divided and created two cells with repaired dna.
b. the cell couldnt divide, and cell division stopped.
c. the cell died before it could complete division.
d. the cell divided and created two nonidentical cells.
e. the cell continued to divide uncontrollably to create more damaged cells.

Explanation:

The G2 checkpoint's key role is verifying that DNA replication is complete and undamaged before the cell enters mitosis. If it fails with damaged DNA present:

• Option A is wrong because the checkpoint failure means damaged DNA isn't repaired before division.
• Option B is wrong because the checkpoint failing removes the block to division, so the cell will attempt to divide.
• Option C is wrong because G2 checkpoint failure doesn't directly cause immediate cell death before division; the cell proceeds to divide with damaged DNA.
• Option D is wrong because nonidentical cells result from issues like crossing over errors, not G2 checkpoint failure with damaged DNA.
• Option E is correct: without the G2 checkpoint halting division to fix DNA damage, the cell divides, passing on damaged DNA. This damaged DNA can disrupt normal cell cycle regulation, leading to uncontrolled division and more damaged cells.

Answer:

E. The cell continued to divide uncontrollably to create more damaged cells.