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Question
- what color are foals with olws?
- in foals with olws, what system fails to form properly?
Question 1
OLWS (Overo Lethal White Syndrome) foals have a white coat color because the genetic condition affects pigmentation and also has severe effects on the digestive system.
Foals with OLWS have a failure in the proper formation of the digestive system (specifically the large intestine, as the condition is associated with aganglionic megacolon, similar to Hirschsprung's disease in humans, where the enteric nervous system development is impaired, leading to issues with the digestive tract structure and function).
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