Question

which statement best shows how primary structure relates to protein function? proteins are sensitive to changes in ph. high temperatures cause proteins to denature. the shape and chemistry of an enzymes active site determine its function. changing one amino acid in the protein hemoglobin causes sickle - cell anemia.

Explanation:

The primary structure of a protein is the sequence of amino - acids. Changing one amino acid in hemoglobin (a protein) is an example of a change in primary structure leading to a disease (sickle - cell anemia), showing how primary structure affects function. The other options are about factors like pH and temperature affecting proteins or about the active - site (related to tertiary structure) rather than primary structure.

Answer:

Changing one amino acid in the protein hemoglobin causes sickle - cell anemia.