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Question
- a woman who is a carrier marries a normal man. show the cross. what is the probability that their children will have hemophilia? what sex will a child in the family with hemophilia be? 10. a woman who has hemophilia marries a normal man. how many of their children will have hemophilia, and what is their sex?
Question 9
Step1: Determine Genotypes
Hemophilia is X - linked recessive. Let \( X^H \) be normal allele, \( X^h \) be hemophilia allele. Carrier woman: \( X^H X^h \), normal man: \( X^H Y \).
Step2: Set Up Punnett Square
| \( X^H \) | \( Y \) | |
|---|---|---|
| \( X^h \) | \( X^H X^h \) | \( X^h Y \) |
Step3: Calculate Probability
Total 4 possible genotypes. Only \( X^h Y \) has hemophilia. So probability \( = \frac{1}{4}=25\% \).
Step4: Determine Sex
\( X^h Y \) is male (has Y chromosome).
Step1: Determine Genotypes
Woman with hemophilia: \( X^h X^h \), normal man: \( X^H Y \).
Step2: Set Up Punnett Square
| \( X^H \) | \( Y \) | |
|---|---|---|
| \( X^h \) | \( X^H X^h \) | \( X^h Y \) |
Step3: Analyze Offspring
Out of 4 offspring, 2 are \( X^h Y \) (hemophilic, male). So half (50%) of children will have hemophilia, and they are male.
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Probability: \( 25\% \) (or \( \frac{1}{4} \)), Sex: Male