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Question
- usually, mrnas containing nonsense mutations are only translated once before being recognized and selectively destroyed. the process whereby the faulty mrnas are destroyed is called a. nonsense execution. b. exon - junction complex. c. nonsense - mediated decay (nmd). d. splicing. e. answers d and d are correct.
Brief Explanations
Nonsense - mediated decay (NMD) is a process that recognizes and selectively destroys mRNAs containing nonsense mutations. These faulty mRNAs are translated once before being destroyed. Splicing is related to the processing of pre - mRNA but not the destruction of mRNAs with nonsense mutations. Exon - junction complex is involved in the surveillance mechanism related to NMD but is not the name of the process of destruction. Nonsense execution is not a relevant term here.
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c. nonsense - mediated decay (NMD)